GT-HapScreen F8

The unique diagnostic kit which can be used to detect genetic diseases and screen the autosomal markers in a single reaction!


The GT-HapScreen F8 kit is developed to detect Factor VIII deficiency or commonly known as Hemophilia A disorder. The kit functions on the principle based on STR markers and QF PCR technique to detect carrier or to be patient by linkage analysis. Use of STR markers makes prenatal diagnosis more accurate and reliable.

Kit components include multiplex PCR primers which are designed from F8 gene. This gene is used commonly in carrier detection and prenatal diagnosis of Factor VIII deficiency. STR markers designed from 5 regions that covers the upstream and downstream of the F8 gene.

This kit is optimised to use DNA samples purified from blood, amniotic fluid, and chorionic villus (CVS).

Along with Factor VIII deficiency detection the GT-HapScreen F8 kit includes autosomal STR markers for Chromosome 21, 18, 13, X and Y. These markers provide extra advantages along with detection of this disorder.

  • Avoidance of sample cross-contamination
  • Ruling out maternal cell contamination
  • Sex-determination
  • Paternity testing
  • Chromosomal anueploidy detection

Know more about Factor VIII deficiency
Know more about F8 gene

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